Miga1 | mitoguardin 1

GeneMGI:1924567Synonyms: Fam73a, Mita1, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological

15 No significant impact

6 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:70Adult tissues
0Embryo tissues

Phenotypes

cataract1 supporting datasetMiga1tm1b(EUCOMM)WtsihomozygoteEarly adult6.14x10-8 
hyperactivity2 supporting datasetsMiga1tm1b(EUCOMM)WtsihomozygoteEarly adult4.71x10-6 
decreased vertical activity1 supporting datasetMiga1tm1b(EUCOMM)WtsihomozygoteEarly adult1.91x10-7 
increased startle reflex1 supporting datasetMiga1tm1b(EUCOMM)WtsihomozygoteEarly adult5.91x10-5 
abnormal lens morphology2 supporting datasetsMiga1tm1b(EUCOMM)WtsihomozygoteEarly adult1.45x10-8 
increased circulating alkaline phosphatase level1 supporting datasetMiga1tm1b(EUCOMM)WtsihomozygoteEarly adult2.54x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Miga1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Miga1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Miga1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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