Sun1 | Sad1 and UNC84 domain containing 1

GeneMGI:1924303Synonyms: 4632417G13Rik, Unc84a, +1 more

Physiological systems

20 / 24 physiological systems tested

12 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Adipose tissue Growth/size/body region Nervous system Vision/eye Hearing/vestibular/ear Hematopoietic system Behavior/neurological Cardiovascular system

8 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:22Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased leukocyte cell number	1 supporting dataset	Sun1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4x10^-5
increased neutrophil cell number	1 supporting dataset	Sun1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	6.34x10^-5
decreased total retina thickness	2 supporting datasets	Sun1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.45x10^-17
abnormal auditory brainstem response	5 supporting datasets	Sun1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.23x10^-7
small testis	1 supporting dataset	Sun1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased total body fat amount	2 supporting datasets	Sun1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.02x10^-8
abnormal retina outer nuclear layer morphology	2 supporting datasets	Sun1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.6x10^-21
increased circulating phosphate level	1 supporting dataset	Sun1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.85x10^-5
abnormal startle reflex	1 supporting dataset	Sun1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.66x10^-5
decreased prepulse inhibition	8 supporting datasets	Sun1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.79x10^-49

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sun1.

Associated images

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Histopathology

There is no histopathology data found for Sun1.

IMPC related publications

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External links

No external links available for Sun1.

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*Sun1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Sun1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Sun1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Sun1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Sun1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Sun1^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Sun1^{tm43601(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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