Bcl7a | B cell CLL/lymphoma 7A

GeneMGI:1924295Synonyms: 4432415N06Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Embryo Growth/size/body region Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



unresponsive to tactile stimuli	1 supporting dataset	Bcl7a^{tm1b(EUCOMM)Wtsi}	heterozygote	E18.5	N/A ^*
unresponsive to tactile stimuli	1 supporting dataset	Bcl7a^{tm1b(EUCOMM)Wtsi}	homozygote	E18.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Bcl7a^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Bcl7a^{tm1b(EUCOMM)Wtsi}	homozygote	E18.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bcl7a.

Associated images

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Histopathology

There is no histopathology data found for Bcl7a.

IMPC related publications

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External links

No external links available for Bcl7a.

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*Bcl7a^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Bcl7a^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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