Katnal2 | katanin p60 subunit A-like 2

GeneMGI:1924234Synonyms: 4933439B08Rik, 3110023G01Rik

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Digestive/alimentary Hematopoietic system Renal/urinary system

12 No significant impact

4 Not tested

Gene metrics:13Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased monocyte cell number1 supporting datasetKatnal2em1(IMPC)TcphomozygoteLate adult6.86x10-5 
enlarged stomach1 supporting datasetKatnal2em1(IMPC)TcphomozygoteLate adultN/A * 
abnormal uterus morphology1 supporting datasetKatnal2em1(IMPC)TcphomozygoteLate adultN/A * 
enlarged urinary bladder2 supporting datasetsKatnal2em1(IMPC)TcphomozygoteLate adultN/A * 
small spleen1 supporting datasetKatnal2em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal pancreas morphology1 supporting datasetKatnal2em1(IMPC)TcphomozygoteLate adultN/A * 
enlarged spleen1 supporting datasetKatnal2em1(IMPC)TcphomozygoteLate adultN/A * 
increased circulating alkaline phosphatase level1 supporting datasetKatnal2em1(IMPC)TcphomozygoteEarly adult3.57x10-7 
enlarged lymph nodes1 supporting datasetKatnal2em1(IMPC)TcphomozygoteLate adultN/A * 
male infertility1 supporting datasetKatnal2em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Katnal2em1(IMPC)TcpExon Deletionmouse
Katnal2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Katnal2tm84388(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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