Ifi27l2a | interferon, alpha-inducible protein 27 like 2A

GeneMGI:1924183Synonyms: 2310061N23Rik, Ifi27

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Vision/eye Cardiovascular system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal cornea morphology	1 supporting dataset	Ifi27l2a^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.09x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Ifi27l2a^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.07x10^-5
abnormal retina morphology	1 supporting dataset	Ifi27l2a^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.68x10^-7
abnormal tail length	1 supporting dataset	Ifi27l2a^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.72x10^-6
abnormal retina vasculature morphology	1 supporting dataset	Ifi27l2a^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.06x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Ifi27l2a^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.98x10^-5
abnormal lens morphology	1 supporting dataset	Ifi27l2a^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.8x10^-5
increased circulating bilirubin level	1 supporting dataset	Ifi27l2a^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.42x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ifi27l2a.

Associated images

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Histopathology

There is no histopathology data found for Ifi27l2a.

IMPC related publications

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External links

No external links available for Ifi27l2a.

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*Ifi27l2a^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Ifi27l2a^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Ifi27l2a^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ifi27l2a^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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