Ppfia3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3

GeneMGI:1924037Synonyms: 2410127E16Rik, Liprin-alpha3

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity9 supporting datasetsPpfia3em1(IMPC)JhomozygoteEarly adult8.55x10-32 
increased vertical activity1 supporting datasetPpfia3em1(IMPC)JhomozygoteEarly adult2.79x10-10 
irregularly shaped pupil1 supporting datasetPpfia3em1(IMPC)JhomozygoteEarly adult1.54x10-5 
abnormal vocalization1 supporting datasetPpfia3em1(IMPC)JhomozygoteEarly adult4.94x10-5 
increased exploration in new environment1 supporting datasetPpfia3em1(IMPC)JhomozygoteEarly adult5x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ppfia3em1(IMPC)JExon Deletionmouse
Ppfia3tm42352(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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