Snx27 | sorting nexin family member 27
Physiological systems
22 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Mortality/aging Craniofacial
18 No significant impact
2 Not tested
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
50Embryo tissues
| decreased hemoglobin content | 1 supporting dataset | Snx27tm1b(KOMP)Wtsi | heterozygote | Early adult | 2.24x10-5 | ||
| edema | 1 supporting dataset | Snx27tm1b(KOMP)Wtsi | homozygote | E15.5 | N/A * | ||
| decreased hematocrit | 1 supporting dataset | Snx27tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.97x10-5 | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Snx27tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal craniofacial morphology | 1 supporting dataset | Snx27tm1b(KOMP)Wtsi | homozygote | E15.5 | N/A * | ||
| decreased erythrocyte cell number | 1 supporting dataset | Snx27tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.49x10-6 |
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External links
No external links available for Snx27.
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| Snx27tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Snx27tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Snx27tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |