Gins4 | GINS complex subunit 4
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Vision/eye Behavior/neurological Mortality/aging
17 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues
| microphthalmia | 1 supporting dataset | Gins4tm1b(EUCOMM)Hmgu | heterozygote | Early adult | N/A * | ||
| increased startle reflex | 1 supporting dataset | Gins4tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.65x10-9 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Gins4tm1b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Gins4tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| abnormal retina outer nuclear layer morphology | 2 supporting datasets | Gins4tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 7.43x10-6 | ||
| decreased total retina thickness | 2 supporting datasets | Gins4tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.32x10-6 | ||
| abnormal retina morphology | 1 supporting dataset | Gins4tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 7.1x10-5 |
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External links
No external links available for Gins4.
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| Gins4tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Gins4tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Gins4tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |