Unc5cl | unc-5 family C-terminal like

GeneMGI:1923839Synonyms: 2510009H09Rik

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Integument Endocrine/exocrine gland Vision/eye Behavior/neurological

14 No significant impact

4 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology1 supporting datasetUnc5clem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal skin morphology1 supporting datasetUnc5clem1(IMPC)MbphomozygoteLate adultN/A * 
decreased locomotor activity2 supporting datasetsUnc5clem1(IMPC)MbphomozygoteEarly adult1.02x10-5 
anophthalmia1 supporting datasetUnc5clem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal ovary morphology1 supporting datasetUnc5clem1(IMPC)MbphomozygoteLate adultN/A * 
increased circulating cholesterol level1 supporting datasetUnc5clem1(IMPC)MbphomozygoteLate adult2.06x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Unc5clem1(IMPC)MbpExon Deletionmouse
Unc5cltm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Unc5cltm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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