Wipi2 | WD repeat domain, phosphoinositide interacting 2

GeneMGI:1923831Synonyms: 1110018O08Rik, 2510001I10Rik

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Mortality/aging

14 No significant impact

8 Not tested

Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance2 supporting datasetsWipi2em1(IMPC)BayhomozygoteEarly adultN/A * 
increased total retina thickness1 supporting datasetWipi2em1(IMPC)BayheterozygoteEarly adult2.76x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Wipi2em1(IMPC)BayExon Deletionmouse
Wipi2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Wipi2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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