Qrsl1 | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1

GeneMGI:1923813Synonyms: GatA, 2700038P16Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Adipose tissue Skeleton Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral content1 supporting datasetQrsl1em1(IMPC)JheterozygoteEarly adult3.88x10-5 
increased total body fat amount1 supporting datasetQrsl1em1(IMPC)JheterozygoteEarly adult5.02x10-5 
preweaning lethality, complete penetrance1 supporting datasetQrsl1em1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Qrsl1em1(IMPC)JExon Deletionmouse
Qrsl1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Qrsl1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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