Cecr2 | CECR2, histone acetyl-lysine reader

GeneMGI:1923799Synonyms: Gtl4, 2810409N01Rik, +2 more

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Embryo Nervous system Behavior/neurological Mortality/aging Cardiovascular system Craniofacial

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

51Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal hindbrain morphology	1 supporting dataset	Cecr2^{tm2b(EUCOMM)Hmgu}	heterozygote	E12.5	N/A ^*
abnormal midbrain morphology	1 supporting dataset	Cecr2^{tm2b(EUCOMM)Hmgu}	heterozygote	E12.5	N/A ^*
abnormal forebrain morphology	1 supporting dataset	Cecr2^{tm2b(EUCOMM)Hmgu}	heterozygote	E12.5	N/A ^*
abnormal midbrain morphology	1 supporting dataset	Cecr2^{tm2b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*
abnormal hindbrain morphology	1 supporting dataset	Cecr2^{tm2b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Cecr2^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal forebrain morphology	1 supporting dataset	Cecr2^{tm2b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*
abnormal craniofacial morphology	1 supporting dataset	Cecr2^{tm2b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*
decreased exploration in new environment	1 supporting dataset	Cecr2^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	5.19x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Cecr2^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	4.79x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cecr2.

Associated images

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Histopathology

There is no histopathology data found for Cecr2.

IMPC related publications

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External links

No external links available for Cecr2.

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*Cecr2^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cecr2^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cecr2^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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