Trappc9 | trafficking protein particle complex 9

GeneMGI:1923760Synonyms: 2900005P22Rik, TRS130, +3 more

Physiological systems

18 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

10 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:19Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased fasting circulating glucose level	1 supporting dataset	Trappc9^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.02x10^-12
decreased CD11b-low dendritic cell number	1 supporting dataset	Trappc9^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased circulating sodium level	1 supporting dataset	Trappc9^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.5x10^-5
increased circulating insulin level	1 supporting dataset	Trappc9^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.94x10^-16
decreased lean body mass	1 supporting dataset	Trappc9^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.12x10^-21
increased Ly6C high monocyte number	1 supporting dataset	Trappc9^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased red blood cell distribution width	1 supporting dataset	Trappc9^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.85x10^-6
decreased grip strength	3 supporting datasets	Trappc9^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.19x10^-7
impaired glucose tolerance	1 supporting dataset	Trappc9^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.11x10^-9
decreased KLRG1-positive NK cell number	1 supporting dataset	Trappc9^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Trappc9.

Associated images

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Histopathology

There is no histopathology data found for Trappc9.

IMPC related publications

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External links

No external links available for Trappc9.

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*Trappc9^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Trappc9^{tm1c(EUCOMM)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse
*Trappc9^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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