Txndc11 | thioredoxin domain containing 11

GeneMGI:1923620Synonyms: EF-hand binding protein 1, 2810408E11Rik, +2 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased thigmotaxis	2 supporting datasets	Txndc11^em1(IMPC)J	homozygote	Early adult	8.12x10^-6
hyperactivity	2 supporting datasets	Txndc11^em1(IMPC)J	homozygote	Early adult	2.97x10^-7
decreased bone mineral content	2 supporting datasets	Txndc11^em1(IMPC)J	homozygote	Early adult	2.27x10^-10
increased circulating cholesterol level	1 supporting dataset	Txndc11^em1(IMPC)J	homozygote	Early adult	6.2x10^-5
abnormal bone structure	1 supporting dataset	Txndc11^em1(IMPC)J	homozygote	Early adult	2.96x10^-9
decreased mean corpuscular hemoglobin	1 supporting dataset	Txndc11^em1(IMPC)J	homozygote	Early adult	1.18x10^-5
decreased locomotor activity	1 supporting dataset	Txndc11^em1(IMPC)J	homozygote	Early adult	2.23x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Txndc11.

Associated images

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Histopathology

There is no histopathology data found for Txndc11.

IMPC related publications

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External links

No external links available for Txndc11.

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*Txndc11^em1(IMPC)J*	Exon Deletion	‌	mouse
*Txndc11^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Txndc11^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Txndc11^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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