Tgds | TDP-glucose 4,6-dehydratase
Physiological systems
22 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Embryo Nervous system Vision/eye Behavior/neurological Mortality/aging Cardiovascular system Renal/urinary system
12 No significant impact
2 Not tested
Data collections
Gene metrics:23Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal eye morphology | 1 supporting dataset | Tgdsem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Tgdsem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal behavior | 1 supporting dataset | Tgdsem1(IMPC)Mbp | heterozygote | Early adult | 2.46x10-22 | ||
| abnormal kidney morphology | 1 supporting dataset | Tgdsem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| decreased thigmotaxis | 2 supporting datasets | Tgdsem1(IMPC)Mbp | heterozygote | Early adult | 1.59x10-27 | ||
| abnormal embryo turning | 1 supporting dataset | Tgdsem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| cataract | 1 supporting dataset | Tgdsem1(IMPC)Mbp | heterozygote | Early adult | 8.94x10-6 | ||
| abnormal vitreous body morphology | 1 supporting dataset | Tgdsem1(IMPC)Mbp | heterozygote | Early adult | 5.94x10-6 | ||
| abnormal somite shape | 1 supporting dataset | Tgdsem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal neural tube morphology | 1 supporting dataset | Tgdsem1(IMPC)Mbp | homozygote | E9.5 | N/A * |
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External links
No external links available for Tgds.
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| Tgdsem1(IMPC)Mbp | Exon Deletion | | mouse |
| Tgdstm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |