Pcnp | PEST proteolytic signal containing nuclear protein
Physiological systems
22 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Reproductive system Integument Embryo Growth/size/body region Nervous system Vision/eye Hearing/vestibular/ear Craniofacial Mortality/aging Cardiovascular system
12 No significant impact
2 Not tested
Data collections
Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal pharyngeal arch morphology | 1 supporting dataset | Pcnpem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal neural tube morphology | 1 supporting dataset | Pcnpem1(IMPC)Mbp | heterozygote | E9.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Pcnpem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal embryo turning | 1 supporting dataset | Pcnpem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal optic vesicle formation | 1 supporting dataset | Pcnpem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| enlarged epididymis | 1 supporting dataset | Pcnpem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Pcnpem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal forebrain development | 1 supporting dataset | Pcnpem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal heart morphology | 1 supporting dataset | Pcnpem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal neural tube morphology | 1 supporting dataset | Pcnpem1(IMPC)Mbp | homozygote | E9.5 | N/A * |
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External links
No external links available for Pcnp.
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| Pcnpem1(IMPC)Mbp | Exon Deletion | | mouse |
| Pcnptm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |