Ndfip2 | Nedd4 family interacting protein 2

GeneMGI:1923523Synonyms: 0710001O20Rik, 9130207N19Rik, +1 more

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye Behavior/neurological Renal/urinary system

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



decreased locomotor activity	2 supporting datasets	Ndfip2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.26x10^-8
cataract	1 supporting dataset	Ndfip2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.74x10^-6
increased grip strength	1 supporting dataset	Ndfip2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.16x10^-5
increased circulating serum albumin level	1 supporting dataset	Ndfip2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.83x10^-6
increased circulating calcium level	1 supporting dataset	Ndfip2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.38x10^-6
abnormal lens morphology	1 supporting dataset	Ndfip2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.28x10^-6
increased vertical activity	1 supporting dataset	Ndfip2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.5x10^-6
increased body length	1 supporting dataset	Ndfip2^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	3.43x10^-5
increased circulating sodium level	1 supporting dataset	Ndfip2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.9x10^-5
abnormal kidney morphology	1 supporting dataset	Ndfip2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ndfip2.

Associated images

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Histopathology

There is no histopathology data found for Ndfip2.

IMPC related publications

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External links

No external links available for Ndfip2.

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*Ndfip2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ndfip2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ndfip2^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell

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