Cyrib | CYFIP related Rac1 interactor B
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Vision/eye Behavior/neurological Mortality/aging
14 No significant impact
5 Not tested
Gene metrics:13Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
60Embryo tissues
edema | 1 supporting dataset | Cyribtm1b(KOMP)Wtsi | homozygote | E15.5 | N/A * | ||
abnormal retina morphology | 1 supporting dataset | Cyribtm1b(KOMP)Wtsi | heterozygote | Early adult | 1.4x10-10 | ||
decreased exploration in new environment | 1 supporting dataset | Cyribtm1b(KOMP)Wtsi | heterozygote | Early adult | 3.01x10-5 | ||
male infertility | 1 supporting dataset | Cyribtm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
abnormal retina morphology | 1 supporting dataset | Cyribtm1b(KOMP)Wtsi | homozygote | Early adult | 1.98x10-5 | ||
preweaning lethality, incomplete penetrance | 3 supporting datasets | Cyribtm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
decreased circulating sodium level | 1 supporting dataset | Cyribtm1b(KOMP)Wtsi | heterozygote | Early adult | 1.49x10-5 |
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External links
No external links available for Cyrib.
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Cyribtm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Cyribtm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Cyribtm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |