Jakmip2 | janus kinase and microtubule interacting protein 2

GeneMGI:1923467Synonyms: D930046L20Rik, 6430702L21Rik

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hearing/vestibular/ear Hematopoietic system Behavior/neurological Mortality/aging

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating glucose level1 supporting datasetJakmip2em1(IMPC)JhomozygoteEarly adult6.24x10-8 
preweaning lethality, incomplete penetrance1 supporting datasetJakmip2em1(IMPC)JhomozygoteEarly adultN/A * 
increased leukocyte cell number1 supporting datasetJakmip2em1(IMPC)JhomozygoteEarly adult2.3x10-5 
abnormal auditory brainstem response2 supporting datasetsJakmip2em1(IMPC)JhomozygoteEarly adult1.6x10-5 
hyperactivity6 supporting datasetsJakmip2em1(IMPC)JhomozygoteEarly adult2.76x10-12 
increased startle reflex1 supporting datasetJakmip2em1(IMPC)JhomozygoteEarly adult3.61x10-5 
decreased circulating calcium level1 supporting datasetJakmip2em1(IMPC)JhomozygoteEarly adult6.06x10-7 
decreased anxiety-related response1 supporting datasetJakmip2em1(IMPC)JhomozygoteEarly adult9.94x10-6 
decreased circulating bilirubin level1 supporting datasetJakmip2em1(IMPC)JhomozygoteEarly adult2.31x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Jakmip2em1(IMPC)JIntra-exon deletionmouse

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