Usp31 | ubiquitin specific peptidase 31

GeneMGI:1923429Synonyms: 6330567E21Rik

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Nervous system Vision/eye Hematopoietic system Behavior/neurological

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:20Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity9 supporting datasetsUsp31em1(IMPC)HhomozygoteLate adult2.98x10-19 
increased basophil cell number2 supporting datasetsUsp31em1(IMPC)MarchomozygoteEarly adult7.33x10-51 
increased prepulse inhibition2 supporting datasetsUsp31em1(IMPC)MarchomozygoteEarly adult2.84x10-11 
decreased startle reflex1 supporting datasetUsp31em1(IMPC)HhomozygoteEarly adult6.42x10-6 
abnormal gait1 supporting datasetUsp31em1(IMPC)HhomozygoteEarly adult4.67x10-6 
decreased locomotor activity6 supporting datasetsUsp31em1(IMPC)HhomozygoteEarly adult2.14x10-8 
impaired pupillary reflex1 supporting datasetUsp31em1(IMPC)HhomozygoteLate adult1.15x10-5 
decreased exploration in new environment1 supporting datasetUsp31em1(IMPC)HhomozygoteLate adult3.08x10-8 
tremors1 supporting datasetUsp31em1(IMPC)HhomozygoteLate adult8.45x10-9 
increased circulating phosphate level1 supporting datasetUsp31em1(IMPC)MarchomozygoteEarly adult7.53x10-18 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Usp31em1(IMPC)HExon Deletionmouse
Usp31em1(IMPC)MarcDeletionmouse
Usp31tm1aNarlKO first allele (reporter-tagged insertion with conditional potential)es cell

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