Kdm3b | KDM3B lysine (K)-specific demethylase 3B

GeneMGI:1923356Synonyms: 5830462I21Rik, JHDM2B, +1 more

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Integument Growth/size/body region Nervous system Hematopoietic system Behavior/neurological Skeleton Craniofacial Mortality/aging Cardiovascular system

10 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



hemorrhage	1 supporting dataset	Kdm3b^em1(IMPC)Tcp	homozygote	E18.5	N/A ^*
preweaning lethality, incomplete penetrance	3 supporting datasets	Kdm3b^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal facial morphology	1 supporting dataset	Kdm3b^em1(IMPC)Tcp	homozygote	E18.5	N/A ^*
abnormal skin morphology	1 supporting dataset	Kdm3b^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
decreased body length	1 supporting dataset	Kdm3b^em1(IMPC)Tcp	heterozygote	Early adult	3.27x10^-6
decreased exploration in new environment	2 supporting datasets	Kdm3b^em1(IMPC)Tcp	heterozygote	Early adult	3.75x10^-5
abnormal sternum morphology	1 supporting dataset	Kdm3b^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
increased mean corpuscular volume	1 supporting dataset	Kdm3b^em1(IMPC)Tcp	heterozygote	Early adult	5.15x10^-6
decreased prepulse inhibition	1 supporting dataset	Kdm3b^em1(IMPC)Tcp	heterozygote	Early adult	1.06x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kdm3b.

Associated images

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Histopathology

There is no histopathology data found for Kdm3b.

IMPC related publications

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External links

No external links available for Kdm3b.

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*Kdm3b^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Kdm3b^{tm193161(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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