Fam227b | family with sequence similarity 227, member B

GeneMGI:1923073Synonyms: 4930525F21Rik

Physiological systems

23 / 24 physiological systems tested

12 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Digestive/alimentary Muscle Hematopoietic system Behavior/neurological Skeleton Craniofacial Cardiovascular system

11 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:21Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal duodenum morphology	1 supporting dataset	Fam227b^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Fam227b^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal epididymis morphology	1 supporting dataset	Fam227b^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Fam227b^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
male infertility	1 supporting dataset	Fam227b^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Fam227b^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Fam227b^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal tooth morphology	1 supporting dataset	Fam227b^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged epididymis	1 supporting dataset	Fam227b^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal jejunum morphology	1 supporting dataset	Fam227b^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fam227b.

Associated images

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Histopathology

There is no histopathology data found for Fam227b.

IMPC related publications

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External links

No external links available for Fam227b.

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*Fam227b^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Fam227b^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Fam227b^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Fam227b^{tm39433(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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