4930444P10Rik | RIKEN cDNA 4930444P10 gene

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Vision/eye Hematopoietic system Mortality/aging Cardiovascular system

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina blood vessel morphology1 supporting dataset4930444P10Rikem1(IMPC)TcpheterozygoteEarly adult2.24x10-5 
preweaning lethality, complete penetrance3 supporting datasets4930444P10Rikem1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal retina vasculature morphology1 supporting dataset4930444P10Rikem1(IMPC)TcpheterozygoteEarly adult1.81x10-5 
abnormal retina morphology1 supporting dataset4930444P10Rikem1(IMPC)TcpheterozygoteEarly adult8.91x10-5 
decreased eosinophil cell number1 supporting dataset4930444P10Rikem1(IMPC)TcpheterozygoteEarly adult2.39x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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4930444P10Rikem1(IMPC)TcpExon Deletionmouse

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