Bcl2l12 | BCL2 like 12

GeneMGI:1922986Synonyms: Bcl-L12, 2810475P17Rik, +2 more

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Growth/size/body region Liver/biliary system Hematopoietic system Skeleton

16 No significant impact

3 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

enlarged spleen1 supporting datasetBcl2l12tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased bone mineral content1 supporting datasetBcl2l12tm1.1(KOMP)VlcghomozygoteEarly adult4.57x10-5 
increased spleen weight1 supporting datasetBcl2l12tm1.1(KOMP)VlcghomozygoteEarly adult1.22x10-9 
abnormal spleen morphology1 supporting datasetBcl2l12tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased hematocrit1 supporting datasetBcl2l12tm1.1(KOMP)VlcghomozygoteEarly adult1.94x10-5 
abnormal liver morphology1 supporting datasetBcl2l12tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bcl2l12tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Bcl2l12tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Bcl2l12tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Bcl2l12tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Bcl2l12tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Bcl2l12tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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