Tmem225 | transmembrane protein 225

GeneMGI:1922917Synonyms: 1700030E15Rik

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Reproductive system Immune system Nervous system Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

12 No significant impact

5 Not tested

Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enhanced contextual conditioning behavior1 supporting datasetTmem225em1(IMPC)MbphomozygoteEarly adult2.29x10-5 
cataract1 supporting datasetTmem225em1(IMPC)MbphomozygoteEarly adult6.35x10-5 
small spleen1 supporting datasetTmem225em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal vitreous body morphology1 supporting datasetTmem225em1(IMPC)MbphomozygoteEarly adult5.99x10-5 
small heart1 supporting datasetTmem225em1(IMPC)MbphomozygoteEarly adultN/A * 
male infertility1 supporting datasetTmem225em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal freezing behavior1 supporting datasetTmem225em1(IMPC)MbphomozygoteEarly adult3.28x10-5 
abnormal heart morphology1 supporting datasetTmem225em1(IMPC)MbphomozygoteEarly adultN/A * 
decreased prepulse inhibition1 supporting datasetTmem225em1(IMPC)MbphomozygoteEarly adult6.8x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tmem225em1(IMPC)MbpWhole-gene deletionmouse

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