Fastkd2 | FAST kinase domains 2

GeneMGI:1922869Synonyms: 2810421I24Rik

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Integument Vision/eye Hematopoietic system Mortality/aging

13 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues

Phenotypes

abnormal coat appearance1 supporting datasetFastkd2tm1b(EUCOMM)WtsihomozygoteEarly adult4.2x10-5 
decreased spleen weight1 supporting datasetFastkd2tm1b(EUCOMM)WtsihomozygoteEarly adult2.06x10-5 
decreased total retina thickness1 supporting datasetFastkd2tm1b(EUCOMM)WtsihomozygoteEarly adult1.25x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetFastkd2tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fastkd2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Fastkd2tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Fastkd2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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