Zbtb4 | zinc finger and BTB domain containing 4

GeneMGI:1922830Synonyms: 2310026P19Rik, 9230111I22Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological

14 No significant impact

7 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

abnormal lens morphology1 supporting datasetZbtb4tm1.1(KOMP)VlcghomozygoteEarly adult3.88x10-5 
abnormal sleep behavior2 supporting datasetsZbtb4tm1.1(KOMP)VlcghomozygoteEarly adult2.75x10-5 
hyperactivity5 supporting datasetsZbtb4tm1.1(KOMP)VlcghomozygoteEarly adult1.11x10-5 
persistence of hyaloid vascular system1 supporting datasetZbtb4tm1.1(KOMP)VlcghomozygoteEarly adult5.98x10-6 
fused cornea and lens1 supporting datasetZbtb4tm1.1(KOMP)VlcghomozygoteEarly adult2.01x10-5 
increased circulating chloride level1 supporting datasetZbtb4tm1.1(KOMP)VlcghomozygoteEarly adult4.56x10-9 
increased circulating sodium level1 supporting datasetZbtb4tm1.1(KOMP)VlcghomozygoteEarly adult4.22x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zbtb4tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Zbtb4tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Zbtb4tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Zbtb4tm463064(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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