Eppin | epididymal peptidase inhibitor

GeneMGI:1922776Synonyms: 1700024E17Rik, Spinlw1

Physiological systems

21 / 24 physiological systems tested

11 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Digestive/alimentary Vision/eye Hematopoietic system Mortality/aging Renal/urinary system

10 No significant impact

3 Not tested

Gene metrics:17Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal spleen morphology1 supporting datasetEppinem1(IMPC)MbphomozygoteLate adultN/A * 
enlarged lymph nodes2 supporting datasetsEppinem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal skin morphology1 supporting datasetEppinem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal lymph node morphology2 supporting datasetsEppinem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal vitreous body morphology1 supporting datasetEppinem1(IMPC)MbphomozygoteEarly adult7.3x10-5 
abnormal skin morphology1 supporting datasetEppinem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal testis morphology1 supporting datasetEppinem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal vitreous body morphology1 supporting datasetEppinem1(IMPC)MbphomozygoteLate adult6.27x10-5 
increased circulating creatinine level1 supporting datasetEppinem1(IMPC)MbphomozygoteEarly adult1.31x10-5 
small testis1 supporting datasetEppinem1(IMPC)MbphomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Eppinem1(IMPC)MbpWhole-gene deletionmouse

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