Anapc15 | anaphase promoting complex C subunit 15

GeneMGI:1922680Synonyms: 6330414C15Rik, 3200002M19Rik

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Embryo Growth/size/body region Nervous system Vision/eye Craniofacial Mortality/aging

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic growth retardation	1 supporting dataset	Anapc15^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal placenta size	1 supporting dataset	Anapc15^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Anapc15^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal neural tube closure	1 supporting dataset	Anapc15^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal hindbrain morphology	1 supporting dataset	Anapc15^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal placenta morphology	1 supporting dataset	Anapc15^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
edema	1 supporting dataset	Anapc15^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
abnormal midbrain morphology	1 supporting dataset	Anapc15^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
anophthalmia	1 supporting dataset	Anapc15^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
abnormal embryo size	1 supporting dataset	Anapc15^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Anapc15.

Associated images

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Histopathology

There is no histopathology data found for Anapc15.

IMPC related publications

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External links

No external links available for Anapc15.

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*Anapc15^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Anapc15^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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