Tti1 | TELO2 interacting protein 1

GeneMGI:1922675Synonyms: 2610036D13Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hearing/vestibular/ear Hematopoietic system Mortality/aging

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal auditory brainstem response	1 supporting dataset	Tti1^em1(IMPC)J	heterozygote	Early adult	2.91x10^-5
decreased leukocyte cell number	1 supporting dataset	Tti1^em1(IMPC)J	heterozygote	Early adult	3.11x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Tti1^em1(IMPC)J	homozygote	Early adult	N/A ^*
decreased circulating HDL cholesterol level	1 supporting dataset	Tti1^em1(IMPC)J	heterozygote	Early adult	5.57x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tti1.

Associated images

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Histopathology

There is no histopathology data found for Tti1.

IMPC related publications

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External links

No external links available for Tti1.

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*Tti1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Tti1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Tti1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Tti1^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tti1^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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