Cep43 | centrosomal protein 43

GeneMGI:1922546Synonyms: 4930553O10Rik, Fop, +1 more

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal retina blood vessel morphology	1 supporting dataset	Cep43^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.08x10^-6
decreased mean corpuscular volume	1 supporting dataset	Cep43^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.62x10^-5
abnormal retina vasculature morphology	1 supporting dataset	Cep43^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.99x10^-7
cataract	1 supporting dataset	Cep43^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.03x10^-9
abnormal motor coordination/balance	1 supporting dataset	Cep43^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.69x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Cep43^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal lens morphology	1 supporting dataset	Cep43^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.63x10^-9
increased circulating alkaline phosphatase level	1 supporting dataset	Cep43^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.63x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cep43.

Associated images

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Histopathology

There is no histopathology data found for Cep43.

IMPC related publications

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External links

No external links available for Cep43.

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*Cep43^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cep43^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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