Rnf19b | ring finger protein 19B

GeneMGI:1922484Synonyms: Ibrdc3, 4930555L03Rik, +1 more

Physiological systems

23 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging

16 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



enlarged heart	1 supporting dataset	Rnf19b^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
cornea opacity	1 supporting dataset	Rnf19b^{em1(IMPC)Ccpcz}	heterozygote	Early adult	2.98x10^-5
abnormal retina morphology	1 supporting dataset	Rnf19b^{em1(IMPC)Ccpcz}	heterozygote	Early adult	4.68x10^-5
increased eosinophil cell number	1 supporting dataset	Rnf19b^{em1(IMPC)Ccpcz}	heterozygote	Early adult	5.3x10^-5
abnormal heart morphology	1 supporting dataset	Rnf19b^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
increased heart left ventricle size	1 supporting dataset	Rnf19b^{em1(IMPC)Ccpcz}	heterozygote	Early adult	7.41x10^-5
no spontaneous movement	1 supporting dataset	Rnf19b^{em1(IMPC)Ccpcz}	homozygote	E18.5	N/A ^*
preweaning lethality, incomplete penetrance	1 supporting dataset	Rnf19b^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rnf19b.

Associated images

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Histopathology

There is no histopathology data found for Rnf19b.

IMPC related publications

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External links

No external links available for Rnf19b.

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*Rnf19b^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Rnf19b^{tm271092(L1L2_6XOspnEnh_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Rnf19b^{tm271092(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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