Dusp18 | dual specificity phosphatase 18

GeneMGI:1922469Synonyms: 4930527G07Rik, DUSP20, +2 more

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Growth/size/body region Limbs/digits/tail Behavior/neurological Cardiovascular system

10 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal digit morphology	1 supporting dataset	Dusp18^em1(IMPC)J	homozygote	Late adult	1.6x10^-10
abnormal vocalization	1 supporting dataset	Dusp18^em1(IMPC)J	homozygote	Late adult	1.46x10^-12
abnormal coat/hair pigmentation	2 supporting datasets	Dusp18^em1(IMPC)J	homozygote	Late adult	3.14x10^-9
hyperactivity	5 supporting datasets	Dusp18^em1(IMPC)J	homozygote	Early adult	2.39x10^-10
increased circulating serum albumin level	1 supporting dataset	Dusp18^em1(IMPC)J	homozygote	Late adult	4.47x10^-5
increased heart weight	1 supporting dataset	Dusp18^em1(IMPC)J	homozygote	Late adult	4.84x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dusp18.

Associated images

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Histopathology

There is no histopathology data found for Dusp18.

IMPC related publications

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External links

No external links available for Dusp18.

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*Dusp18^em1(IMPC)J*	Exon Deletion	‌	mouse
*Dusp18^{tm386122(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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