Plb1 | phospholipase B1

GeneMGI:1922406Synonyms: 4930539A06Rik, 4930433E17Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased total body fat amount2 supporting datasetsPlb1em1(IMPC)JhomozygoteEarly adult3.82x10-5 
increased lean body mass1 supporting datasetPlb1em1(IMPC)JhomozygoteEarly adult1.52x10-5 
abnormal locomotor behavior1 supporting datasetPlb1em1(IMPC)JhomozygoteEarly adult7.24x10-5 
hyperactivity4 supporting datasetsPlb1em1(IMPC)JhomozygoteEarly adult3.88x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Plb1em1(IMPC)JExon Deletionmouse
Plb1tm42791(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Plb1tm42791(L1L2_st0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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