Rprd2 | regulation of nuclear pre-mRNA domain containing 2

GeneMGI:1922387Synonyms: 6720469I21Rik, 2810036A19Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Pigmentation Integument Embryo Growth/size/body region Behavior/neurological Mortality/aging

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetRprd2em1(IMPC)JhomozygoteEarly adultN/A * 
abnormal locomotor behavior1 supporting datasetRprd2em1(IMPC)JheterozygoteEarly adult4.61x10-5 
abnormal coat/hair pigmentation1 supporting datasetRprd2em1(IMPC)JheterozygoteEarly adult2.35x10-6 
embryonic lethality prior to tooth bud stage1 supporting datasetRprd2em1(IMPC)JhomozygoteE12.5N/A * 
embryonic growth retardation1 supporting datasetRprd2em1(IMPC)JhomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rprd2em1(IMPC)JExon Deletionmouse

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