Usp38 | ubiquitin specific peptidase 38

GeneMGI:1922091Synonyms: 4631402N15Rik, 4833420O05Rik

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Nervous system Vision/eye Hematopoietic system Behavior/neurological Skeleton

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



decreased lean body mass	2 supporting datasets	Usp38^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.95x10^-15
decreased prepulse inhibition	3 supporting datasets	Usp38^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.97x10^-6
persistence of hyaloid vascular system	1 supporting dataset	Usp38^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2x10^-5
increased total body fat amount	2 supporting datasets	Usp38^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.26x10^-14
thrombocytopenia	1 supporting dataset	Usp38^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.33x10^-7
decreased exploration in new environment	1 supporting dataset	Usp38^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2x10^-5
abnormal bone structure	1 supporting dataset	Usp38^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.55x10^-7
increased mean corpuscular volume	1 supporting dataset	Usp38^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.26x10^-5
decreased circulating creatinine level	1 supporting dataset	Usp38^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.74x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Usp38.

Associated images

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Histopathology

There is no histopathology data found for Usp38.

IMPC related publications

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External links

No external links available for Usp38.

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*Usp38^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Usp38^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Usp38^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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