Pik3cb | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Hematopoietic system
15 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
abnormal coat/hair pigmentation | 1 supporting dataset | Pik3cbtm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.17x10-5 | ||
increased hemoglobin content | 1 supporting dataset | Pik3cbtm1a(EUCOMM)Wtsi | homozygote | Early adult | 5x10-5 | ||
increased mean corpuscular hemoglobin | 1 supporting dataset | Pik3cbtm1a(EUCOMM)Wtsi | heterozygote | Early adult | 6.31x10-5 | ||
decreased circulating creatinine level | 1 supporting dataset | Pik3cbtm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.43x10-6 | ||
increased hemoglobin content | 1 supporting dataset | Pik3cbtm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.97x10-5 | ||
increased mean corpuscular hemoglobin | 1 supporting dataset | Pik3cbtm1a(EUCOMM)Wtsi | homozygote | Early adult | 4.28x10-5 |
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External links
No external links available for Pik3cb.
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Pik3cbtm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Pik3cbtm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
Pik3cbtm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |