Dhcr24 | 24-dehydrocholesterol reductase

GeneMGI:1922004Synonyms: 2310076D10Rik, 3-beta-hydroxysterol delta-24 reductase, +2 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating magnesium level	1 supporting dataset	Dhcr24^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	8.54x10^-5
abnormal behavior	2 supporting datasets	Dhcr24^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.87x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Dhcr24^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dhcr24.

Associated images

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Histopathology

There is no histopathology data found for Dhcr24.

IMPC related publications

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External links

No external links available for Dhcr24.

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*Dhcr24^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dhcr24^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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