Cnep1r1 | CTD nuclear envelope phosphatase 1 regulatory subunit 1
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Growth/size/body region Skeleton Mortality/aging
16 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased bone mineral density | 1 supporting dataset | Cnep1r1em1(IMPC)J | heterozygote | Early adult | 6.35x10-7 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Cnep1r1em1(IMPC)J | homozygote | Early adult | N/A * | ||
decreased lean body mass | 1 supporting dataset | Cnep1r1em1(IMPC)J | heterozygote | Early adult | 9.67x10-5 | ||
decreased bone mineral content | 2 supporting datasets | Cnep1r1em1(IMPC)J | heterozygote | Early adult | 4.38x10-6 | ||
prenatal lethality | 1 supporting dataset | Cnep1r1em1(IMPC)J | homozygote | E18.5 | N/A * | ||
embryonic lethality prior to tooth bud stage | 1 supporting dataset | Cnep1r1em1(IMPC)J | homozygote | E12.5 | N/A * |
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External links
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Cnep1r1em1(IMPC)J | Exon Deletion | | mouse |
Cnep1r1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Cnep1r1tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Cnep1r1tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |