Cnep1r1 | CTD nuclear envelope phosphatase 1 regulatory subunit 1

GeneMGI:1921981Synonyms: 5033428A16Rik, Tmem188

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Growth/size/body region Skeleton Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral density1 supporting datasetCnep1r1em1(IMPC)JheterozygoteEarly adult6.35x10-7 
preweaning lethality, complete penetrance1 supporting datasetCnep1r1em1(IMPC)JhomozygoteEarly adultN/A * 
decreased lean body mass1 supporting datasetCnep1r1em1(IMPC)JheterozygoteEarly adult9.67x10-5 
decreased bone mineral content2 supporting datasetsCnep1r1em1(IMPC)JheterozygoteEarly adult4.38x10-6 
prenatal lethality1 supporting datasetCnep1r1em1(IMPC)JhomozygoteE18.5N/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetCnep1r1em1(IMPC)JhomozygoteE12.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cnep1r1em1(IMPC)JExon Deletionmouse
Cnep1r1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cnep1r1tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cnep1r1tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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