Setmar | SET domain without mariner transposase fusion

GeneMGI:1921979Synonyms: 5830404F24Rik, Etet2

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Vision/eye Hematopoietic system Behavior/neurological Skeleton

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal behavior	1 supporting dataset	Setmar^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.28x10^-7
cataract	1 supporting dataset	Setmar^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.91x10^-5
abnormal eye morphology	1 supporting dataset	Setmar^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.42x10^-7
decreased circulating glycerol level	2 supporting datasets	Setmar^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.62x10^-9
abnormal retina morphology	2 supporting datasets	Setmar^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.35x10^-6
increased circulating triglyceride level	1 supporting dataset	Setmar^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.99x10^-9
increased circulating potassium level	1 supporting dataset	Setmar^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.94x10^-5
abnormal gait	1 supporting dataset	Setmar^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.39x10^-5
abnormal vertebrae morphology	1 supporting dataset	Setmar^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.42x10^-6
thrombocytopenia	1 supporting dataset	Setmar^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.39x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Setmar.

Associated images

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Histopathology

There is no histopathology data found for Setmar.

IMPC related publications

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External links

No external links available for Setmar.

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*Setmar^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse

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