Ttc17 | tetratricopeptide repeat domain 17

GeneMGI:1921819Synonyms: 9130020K17Rik, D2Bwg1005e

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological Cardiovascular system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina blood vessel morphology1 supporting datasetTtc17em1(IMPC)JheterozygoteEarly adult1.79x10-5 
increased circulating cholesterol level1 supporting datasetTtc17em1(IMPC)JhomozygoteEarly adult7.72x10-6 
increased startle reflex1 supporting datasetTtc17em1(IMPC)JhomozygoteEarly adult8.41x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ttc17em1(IMPC)JExon Deletionmouse
Ttc17tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ttc17tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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