Mau2 | MAU2 sister chromatid cohesion factor

GeneMGI:1921799Synonyms: A930019L04Rik, 9130404D08Rik

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Growth/size/body region Vision/eye Behavior/neurological Skeleton Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased body length	1 supporting dataset	Mau2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	5.22x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Mau2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
vertebral transformation	1 supporting dataset	Mau2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	7.17x10^-5
cataract	1 supporting dataset	Mau2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.08x10^-6
absent pinna reflex	1 supporting dataset	Mau2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.34x10^-5
abnormal lens morphology	1 supporting dataset	Mau2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.08x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mau2.

Associated images

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Histopathology

There is no histopathology data found for Mau2.

IMPC related publications

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External links

No external links available for Mau2.

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*Mau2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Mau2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Mau2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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