Mgme1 | mitochondrial genome maintenance exonuclease 1
Physiological systems
17 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Adipose tissue Growth/size/body region Hematopoietic system Skeleton
10 No significant impact
7 Not tested
Data collections
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased mean corpuscular hemoglobin | 1 supporting dataset | Mgme1em1(IMPC)J | homozygote | Early adult | 2.41x10-5 | ||
| increased fasting circulating glucose level | 1 supporting dataset | Mgme1em1(IMPC)J | homozygote | Early adult | 4.43x10-7 | ||
| decreased total body fat amount | 1 supporting dataset | Mgme1em1(IMPC)J | homozygote | Late adult | 3.15x10-8 | ||
| improved glucose tolerance | 1 supporting dataset | Mgme1em1(IMPC)J | homozygote | Late adult | 1.23x10-5 | ||
| abnormal coat/hair pigmentation | 1 supporting dataset | Mgme1em1(IMPC)J | homozygote | Late adult | 1.61x10-6 | ||
| increased bone mineral content | 1 supporting dataset | Mgme1em1(IMPC)J | homozygote | Late adult | 2.5x10-8 | ||
| increased lean body mass | 1 supporting dataset | Mgme1em1(IMPC)J | homozygote | Late adult | 3.07x10-7 |
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External links
No external links available for Mgme1.
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| Mgme1em1(IMPC)J | Exon Deletion | | mouse |
| Mgme1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Mgme1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |