Fam234b | family with sequence similarity 234, member B

GeneMGI:1921775Synonyms: 8430419L09Rik

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin concentration1 supporting datasetFam234btm1a(EUCOMM)WtsihomozygoteEarly adult5.88x10-5 
decreased hemoglobin content1 supporting datasetFam234btm1a(EUCOMM)WtsihomozygoteEarly adult3.58x10-7 
decreased T cell number1 supporting datasetFam234btm1a(EUCOMM)WtsihomozygoteEarly adult6.07x10-5 
decreased CD8-positive, alpha-beta T cell number1 supporting datasetFam234btm1a(EUCOMM)WtsihomozygoteEarly adult3.98x10-7 
increased circulating calcium level1 supporting datasetFam234btm1a(EUCOMM)WtsihomozygoteEarly adult1.16x10-6 
decreased circulating triglyceride level1 supporting datasetFam234btm1a(EUCOMM)WtsihomozygoteEarly adult1.55x10-7 
increased B cell number1 supporting datasetFam234btm1a(EUCOMM)WtsihomozygoteEarly adult6.95x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fam234btm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Fam234btm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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