Tnks2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2

GeneMGI:1921743Synonyms: 5430432P15Rik, Parp5b

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Pigmentation Integument Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



increased grip strength	1 supporting dataset	Tnks2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.98x10^-5
increased startle reflex	1 supporting dataset	Tnks2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.41x10^-5
abnormal coat/hair pigmentation	1 supporting dataset	Tnks2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.7x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tnks2.

Associated images

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Histopathology

There is no histopathology data found for Tnks2.

IMPC related publications

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External links

No external links available for Tnks2.

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*Tnks2^{tm1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Tnks2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tnks2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tnks2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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