Exoc3l2 | exocyst complex component 3-like 2

GeneMGI:1921713Synonyms: 4933417E01Rik, Gm19857

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Behavior/neurological Skeleton Cardiovascular system Craniofacial Mortality/aging

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

1Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



abnormal cranium morphology	1 supporting dataset	Exoc3l2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.34x10^-7
increased circulating serum albumin level	1 supporting dataset	Exoc3l2^em1(IMPC)J	heterozygote	Early adult	5.14x10^-5
abnormal embryo size	1 supporting dataset	Exoc3l2^em1(IMPC)J	homozygote	E18.5	N/A ^*
increased circulating iron level	1 supporting dataset	Exoc3l2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	8.17x10^-5
impaired glucose tolerance	1 supporting dataset	Exoc3l2^em1(IMPC)J	heterozygote	Early adult	8.64x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Exoc3l2^em1(IMPC)J	homozygote	Early adult	N/A ^*
decreased heart weight	1 supporting dataset	Exoc3l2^em1(IMPC)J	heterozygote	Early adult	6.55x10^-6
abnormal tooth morphology	1 supporting dataset	Exoc3l2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.98x10^-6
decreased grip strength	2 supporting datasets	Exoc3l2^em1(IMPC)J	heterozygote	Early adult	2.81x10^-6
abnormal incisor morphology	1 supporting dataset	Exoc3l2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.43x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Exoc3l2.

Associated images

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Histopathology

There is no histopathology data found for Exoc3l2.

IMPC related publications

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External links

No external links available for Exoc3l2.

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*Exoc3l2^em1(IMPC)J*	Exon Deletion	‌	mouse
*Exoc3l2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Exoc3l2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Exoc3l2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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