Ubap2l | ubiquitin-associated protein 2-like

GeneMGI:1921633Synonyms: NICE-4, 4932431F02Rik, +2 more

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Embryo Growth/size/body region Limbs/digits/tail Skeleton Cardiovascular system Mortality/aging

11 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsUbap2lem1(IMPC)BayhomozygoteEarly adultN/A * 
short tibia1 supporting datasetUbap2lem1(IMPC)BayheterozygoteEarly adult7.86x10-5 
abnormal body wall morphology1 supporting datasetUbap2lem1(IMPC)BayhomozygoteE18.5N/A * 
prolonged RR interval1 supporting datasetUbap2lem1(IMPC)BayheterozygoteEarly adult2.53x10-5 
decreased heart rate1 supporting datasetUbap2lem1(IMPC)BayheterozygoteEarly adult8.49x10-5 
abnormal embryo size1 supporting datasetUbap2lem1(IMPC)BayhomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ubap2lem1(IMPC)BayExon Deletionmouse
Ubap2ltm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ubap2ltm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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