Hsf2bp | heat shock transcription factor 2 binding protein

GeneMGI:1921627Synonyms: 4932437G14Rik

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Limbs/digits/tail Hematopoietic system Behavior/neurological Renal/urinary system

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



increased hemoglobin content	1 supporting dataset	Hsf2bp^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.55x10^-5
oligodactyly	1 supporting dataset	Hsf2bp^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	8.22x10^-10
decreased blood urea nitrogen level	1 supporting dataset	Hsf2bp^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	1.26x10^-5
increased body weight	1 supporting dataset	Hsf2bp^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.98x10^-5
abnormal behavior	1 supporting dataset	Hsf2bp^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.73x10^-7
abnormal behavior	1 supporting dataset	Hsf2bp^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	6.92x10^-5
increased circulating potassium level	1 supporting dataset	Hsf2bp^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	6.02x10^-8
small testis	1 supporting dataset	Hsf2bp^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal urination	1 supporting dataset	Hsf2bp^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	8.32x10^-5
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Hsf2bp^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hsf2bp.

Associated images

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Histopathology

There is no histopathology data found for Hsf2bp.

IMPC related publications

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External links

No external links available for Hsf2bp.

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*Hsf2bp^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Hsf2bp^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Hsf2bp^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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