Rptor | regulatory associated protein of MTOR, complex 1

GeneMGI:1921620Synonyms: raptor, Rap, +1 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Mortality/aging Cardiovascular system

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

21Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to tooth bud stage	1 supporting dataset	Rptor^{tm2b(EUCOMM)Wtsi}	homozygote	E12.5	N/A ^*
abnormal sinus arrhythmia	1 supporting dataset	Rptor^{tm2b(EUCOMM)Wtsi}	heterozygote	Early adult	5.08x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Rptor^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rptor.

Associated images

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Histopathology

There is no histopathology data found for Rptor.

IMPC related publications

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External links

No external links available for Rptor.

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*Rptor^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Rptor^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Rptor^{tm2b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rptor^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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