Lonrf3 | LON peptidase N-terminal domain and ring finger 3

GeneMGI:1921615Synonyms: 4932412G04Rik, Rnf127, +2 more

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:90Adult tissues

0Embryo tissues

Phenotypes

Zygosity:



increased circulating magnesium level	1 supporting dataset	Lonrf3^{tm1a(KOMP)Wtsi}	hemizygote	Early adult	1.28x10^-6
increased circulating free fatty acids level	1 supporting dataset	Lonrf3^{tm1a(KOMP)Wtsi}	hemizygote	Early adult	6.57x10^-7
increased circulating calcium level	1 supporting dataset	Lonrf3^{tm1a(KOMP)Wtsi}	homozygote	Early adult	9.17x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lonrf3.

Associated images

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Histopathology

There is no histopathology data found for Lonrf3.

IMPC related publications

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External links

No external links available for Lonrf3.

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*Lonrf3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Lonrf3^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Lonrf3^{tm41056(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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